Inflammatory Myofibroblastic Tumor at base of Tongue: A Case Report

Abstract

Introduction: The inflammatory myofibroblastic tumor is a rare type of tumor more commonly located at the lungs, abdomen, and pelvis, rarely located at head and neck. The etiology and pathogenesis remain elusive but 50% of the cases involve ALK locus on the 2p23 gene.

The study was previously reviewed and approved by the University’s Ethics and Research Committees, receiving the registration number 0T14-004.

Case presentation: We report a 43-year-old male presented with large inflammatory myofibroblastic tumor at the base of the tongue, the patient referred dysphagia and dysphonia. He had a history of two partial resections and radiotherapy. A complete excision was performed. Satisfactory postsurgical outcome and 6-month follow-up.

Conclusion: Inflammatory myofibroblastic tumor is rarely located at the head and neck, the occurrence in the oral cavity is unusual even at the tongue. The etiology is still unclear, it has a locally aggressive nature and its growth velocity is variable. Different treatment modalities have been described; however, the complete excision is proven the most effective. Immunohistochemical findings may not establish a final diagnosis.