Lactobacillus plantarum SN13T Cells Improve Hepatic Dysfunction And Fecal Microbiota: A Randomized Pilot Study

Abstract

The liver dysfunction is a worldwide health problem. It has been suggested that an imbalance of gut microbiome is associated with a variety of diseases. The goal of the present clinical trial is to evaluate the effectiveness of Lactobacillus plantarum SN13T on hepatic function and fecal microbiota. This study enrolled 22 subjects, aged between 20 and 70 years, and who had any of the following conditions: 40Bifidobacterium was increased only in the live SN13T group. In conclusion, Lactobacillus plantarum SN13T alters the composition of gut microbiota and improves liver function in subjects with mild liver dysfunction.

This clinical trial was registered with University hospital Medical Information Network Clinical Trials Registry (UMIN-CTR) as UMIN000027440.