Cutaneous Lipomatous Metaplasia in Patient with Severe Atopic Dermatitis in Therapy with Dupilumab

Authors

  • Silvia Mariel Ferrucci
  • Luisa Angileri
  • Simona Tavecchio
  • Emilio Berti
  • Antonina Parafioriti
  • Francesca Boggio
  • Vinicio Boneschi

Abstract

Introduction: Lipomatous Metaplasia (LM) is a well-known aspect associated to a variety of inflammatory and neoplastic processes.

Case presentation: Here, we describe a case of LM arising in a woman during dupilumab treatment. To our knowledge there are no data in the literature about side effects similar to the clinical picture we observed in our patient.

Conclusion: We have supposed that inhibition of IL-4, together with chronic photo-exposure, could have induced the development of mature fatty tissue in the context of a cytokine pattern modified by therapy with dupilumab.

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Published

2022-03-31

How to Cite

Ferrucci, S. M., Angileri, L., Tavecchio, S., Berti, E., Parafioriti, A., Boggio, F., & Boneschi, V. (2022). Cutaneous Lipomatous Metaplasia in Patient with Severe Atopic Dermatitis in Therapy with Dupilumab. Archives of Clinical and Biomedical Research, 6(2), 342–346. Retrieved from https://fortunejournals.org/ojs/index.php/acbr/article/view/14916