Unusual Presentation of Alport Syndrome in a Female Patient without Hematuria with affected all Male Offspring: A Rare Case Report

Abstract

Alport syndrome (AS) is an inherited disorder mainly involves basement membrane clinically characterized by hematuria, deafness and visual abnormalities. Males are mostly affected. Here we present a case of 40 years old female who has family history of renal impairment, hypertension, hearing loss presented with nephrotic range proteinuria and renal impairment. After evaluation she was subsequently diagnosed as a case of Alport syndrome with ESRD.